Treatment Outcome of Early-stage Laryngeal Carcinoma Treated with Radical Radiotherapy Using Different Techniques: A Retrospective Study

Tavseef Ahmad Tali; Fiza Amin; Javaid Ahmad Dar; Shahid Rashid Sofi; Mushtaq Ahmad Sofi; Nazir Ahmad Khan; Nazir Ahmad Dar

doi:10.31557/apjcc.2023.8.2.269-273

Authors

Tavseef Ahmad Tali Radiation Oncology, Sher-I-Kashmir Institute of Medical Sciences Skims Soura Srinagar, India.
Fiza Amin Gynaecology and Obstetrics, Skims Medical College Srinagar, India.
Javaid Ahmad Dar Department of Cardiology, Christian Medical College Vellore, India.
Shahid Rashid Sofi Radiation Oncology, Sher-I-Kashmir Institute of Medical Sciences Skims Soura Srinagar, India.
Mushtaq Ahmad Sofi Radiation Oncology, Sher-I-Kashmir Institute of Medical Sciences Skims Soura Srinagar, India.
Nazir Ahmad Khan Radiation Oncology, Sher-I-Kashmir Institute of Medical Sciences Skims Soura Srinagar, India.
Nazir Ahmad Dar Statistcian Pbcr Sher-I-Kashmir Institute of Medical Sciences Skims Soura Srinaga, India.

DOI:

https://doi.org/10.31557/apjcc.2023.8.2.269-273

Keywords:

Radical radiotherapy, Overall survival (OS), Diseases free survival (DFS).

Abstract

Aim: The aim was to evaluate the treatment outcomes and prognostic characteristics of patients with early-stage glottic laryngeal carcinoma who underwent radical radiotherapy (RT) with different techniques.
Materials and Methods: Radiotherapy was applied using the 2D conventional technique, 3DCRT (three dimensional conformal radiotherapy and IMRT (intensity modulated radiation therapy). Clinical T stages were 12 (48%) for T1a, 5 (20%) for T1b and 8 (32%) for T2. Stage and anterior commissure involvement were analyzed as prognostic factors.
Results: There were 12 (48%) patients with T1a, 5 (20%) patients with T1b and 8 (32%) patients with T2 cancer. 5 years of overall survival and diseases free survival for T1a, T1b, T2 were found to be 91%, 80%, 62% and 91%, 80%, 62% respectively. 5 year survival for patients without and with involvement of anterior commissure was 92% and 67% respectively. Hence, showing poor survival in patients with T2 lesion or T1 lesion with involvement of anterior commissure.
Conclusion: In early-stage laryngeal carcinomas, radical RT is a function sparing and effective treatment modality with excellent survival rates, regardless of treatment techniques.