TY - JOUR AU - Miluska Castillo AU - Luis Bernabe AU - Carlos Castaneda AU - Nancy Suarez AU - Fernando Barreda AU - Daniel Valdivia AU - Eloy Ruiz AU - Jais Nieves AU - Emmanuel Dias-Neto AU - Maria Landa-Baella AU - Jennifer Montano-Flores AU - Ivan Chavez PY - 2021/03/26 Y2 - 2024/03/28 TI - Prevalence of H. pylori Infection in Relatives of Peruvian Patients with Gastric Cancer JF - Asian Pacific Journal of Cancer Care JA - apjcc VL - 6 IS - 1 SE - Original Research DO - 10.31557/apjcc.2021.6.1.53-57 UR - http://www.waocp.com/journal/index.php/apjcc/article/view/602 AB - Objective: The aim of this study was to determine the relationship between Helicobacter pylori (H. pylori) infection in relatives and patients with gastric cancer (GC).Methods: H. pylori infection was evaluated by the breath urease test in 171 relatives and by qPCR technique in gastric tissue of 61 patients (n=45 for GC and n=16 for non-GC). Results: There were included 137 relatives of GC patients and 34 of non-GC. The median age of the relatives of patients with a gastric tissue sample was 39 years (10-86). Infection was found in 60.2% (n=103) relatives. There were no higher H. pylori infection rates in relatives of patients with gastric cancer (62% vs 62.9%, p=0.33), H. pylori infection (60% vs 60%, p=0.96), or metaplasia (58.8% vs 61.8%, p=0.71). Conclusion: The prevalence of infection in relatives of GC patients is high in our population but not associated with H. pylori presence in the paired case. ER -