TY - JOUR AU - Budhadev Baral AU - Kartik Muduli AU - Shweta Jakhmola AU - Sabyasachi Parida AU - Selvakumar Elangovan AU - Nirmal Kumar Mohakud AU - Hem Chandra Jha PY - 2021/10/26 Y2 - 2024/03/28 TI - COVID-19 Severity among Cancer-COVID Patients with Different Types of Cancer: A Case Series of Five Patients JF - Asian Pacific Journal of Cancer Care JA - apjcc VL - 6 IS - S1 SE - Case series DO - 10.31557/apjcc.2021.6.S1.117-122 UR - http://www.waocp.com/journal/index.php/apjcc/article/view/685 AB - Background: People with malignancy are under increased threat in the current COVID-19 pandemic. It is crucial to study the severity of COVID-19 in different cancer type as the microenvironments are different. Besides, the effect on specific organs should be studied to understand the long-term consequences of both the diseases and its treatment. Methods: In our retrospective case series, we are presenting degree of severity in 5 cancer-COVID patients based on their clinical characteristics. All the patients were RT-PCR confirmed COVID-19 patients with malignancy. The demographic and clinical data of the patients were retrieved from the hospital database.Results: The cancers include; stomach (1), bladder (2), glioma (3), lungs (4) and hard palate cancer (5). Patient-4 and 5 were receiving chemotherapy when they got infected and had highly dysregulated liver function and higher CT severity score (19/25) compared to the nonrecipients. In patient-2 inflammatory and other haematological parameters we highly dysregulated suggesting a possible bottle neck of older age. Interestingly in the patient-3 the COVID-19 markers like lymphocyte, neutrophil and platelet levels were close to or within the normal limits unlike other patients. Conclusions: All the patents included in our report died during hospitalization. The patients receiving chemotherapy had possible impaired liver function and died early compared to the nonrecipients. The characteristic COVID-19 markers like lymphopenia, neutrophilia and thrombocytopenia did not occur in the glioma patient. The effect of cancer-COVID and its treatment on specific organs like the liver and kidney need to be studied during treatment and follow-up.  ER -