The Role of Ubiquitin-specific Peptidases in Colorectal Cancer: A Systematic Review Protocol

Authors

  • Eman Al-Balushi College of Health Sciences, University of Sharjah, Sharjah, UAE.
  • Amina Al-Marzouqi College of Health Sciences, University of Sharjah, Sharjah, UAE.
  • Shima Tavoosi Department of Biology, Faculty of Sciences, University of Isfahan, Hezar Jerib Ave., Azadi Square, Isfahan, 81746-73441, Iran. Department of Cellular and Molecular Biology, Islamic Azad University Tehran Medical Sciences, Tehran, Iran.
  • Amir Hossein Baghsheikhi Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran. Department of Cellular and Molecular Biology, Islamic Azad University Tehran Medical Sciences, Tehran, Iran.
  • Arash Sadri Lyceum Scientific Charity. Students’ Scientific Research Center, Tehran University of Medical Sciences, Tehran, Iran.
  • Leyla Sharifi Aliabadi Cell Therapy and Hematopoietic Stem Cell Transplantation Research Center, Research Institute for Oncology, Hematology, and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran.
  • Mohammad-Mahdi Salarabedi Student Research committee, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Syed Azizur Rahman College of Health Sciences, University of Sharjah, Sharjah, UAE.
  • Nabeel Al-Yateem College of Health Sciences, University of Sharjah, Sharjah, UAE.
  • Alizera Mosavi Jarrahi Cancer Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Aram Halimi Department of Epidemiology, School of Public Health and Safety, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Endocrine Research Center, Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
  • Mohammad Ahmadvand Cell Therapy and Hematopoietic Stem Cell Transplantation Research Center, Research Institute for Oncology, Hematology, and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran.
  • Wael M Abdel-Rahman Department of Medical Laboratory Sciences, College of Health Sciences; and Research Institute of Medical and Health Sciences, University of Sharjah, Sharjah, UAE.

Keywords:

Colorectal Cancer- Ubiquitin-specific Peptidases- Protocol

Abstract

Background: This systematic review aims to comprehensively assess and synthesize the current body of evidence regarding the role of ubiquitin-specific peptidases in colorectal cancer.
Methods: This protocol adhered to the guidelines outlined in the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Protocol (PRISMA-P) and was officially registered with the International Prospective Register for Systematic Reviews (PROSPERO) under the registration number CRD42022348183.
Results: This study will provide a concise summary of the synthesized data from the included studies and will synthesize key findings, explore clinical and therapeutic implications, address limitations and gaps in knowledge, and propose avenues for future research.
Conclusion: This section will conclude by summarizing the key takeaways from the systematic review and emphasizing the relevance of the findings in advancing our knowledge of the role of USPs in colorectal cancer. It will also underscore the potential implications for clinical practice and future research directions.

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Published

2023-10-07

Issue

Vol. 8 No. 4 (2023)

Section

Study Protocol

License

 West Asia Organization for Cabcer Prevention retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License 4 (This permits anyone to copy, distribute, transmit and adapt the published work, provided the original work and source are appropriately cited).