Pattern of Colorectal Cancer in Karbala Province of Iraq: Data from Developing Country

Ahmed Mjali; Sabah Kareem Hamzah; Lamya A A Darwish; Ali Tahseen Ali Al-Rubai

doi:10.31557/apjec.2024.7.1.15-19

Authors

Ahmed Mjali Department of Hematology /Oncology, Al- Hussein Medical City, Karbala, Iraq.
Sabah Kareem Hamzah Department of Surgery, Al- Hussein Medical City, Karbala, Iraq.
Lamya A A Darwish Department of Internal Medicine, College of Medicine, University of Al-Ameed, Karbala, Iraq.
Ali Tahseen Ali Al-Rubai Drug Discovery and Development Department, College of Pharmacy and Pharmaceutical Sciences, University of Sunderland, Sunderland, United Kingdom.

DOI:

https://doi.org/10.31557/apjec.2024.7.1.15-19

Keywords:

Colorectal cancer - Pattern- Karbala- Iraq

Abstract

Background: Globally, there are differences in the prevalence of colorectal cancer (CRC) depending on environmental and demographic factors.

Objective: Our study’s objective was to analyze the CRC pattern in the Iraqi province of Karbala, comparing and identifying probable variations with another people.

Methods: In Iraq, at the Al-Hussein Cancer Center in Karbala, retrospective descriptive research was conducted on 524 patients who diagnosed with CRC from January 2012 to December 2020.

Results: The incidence rate of CRC increased from 3.83 per 100,000 in 2012 to 5.69 per 100,000 in 2020. Among our patients, median age was 55 years. The proportion of males was (54.96%) while the proportion of females was (45.04%) with a M:F ratio of (1.22:1). The most affected anatomical site was colon in (64.89%) and adenocarcinoma was the most frequent histopathology in (67.18%). Unfortunately, more than 46% of cases presented as stage III & IV.

Conclusion: This statistical analysis of CRC could be a fundamental knowledge source to analyze epidemiological pattern, to assess development in the last few years and to improve treatment plans.