Comparative Study between Therapeutic Mammoplasty and Conventional Breast-Conserving Surgery in Early-Stage Breast Cancer

Mohammed Siam; Youssef Hassan; Hossam Hassan Kamel Hassan; Mohamed Mokhtar; Esayed Elmokadem; Samia Hussein; Mayada El-metwally Ibrahim

doi:10.31557/APJCC.2026.11.5.749

Authors

Mohammed Siam General Surgery Department, Faculty of Medicine, Suez University, Egypt.
Youssef Hassan Plastic Surgery unit, General Surgery Department, Faculty of Medicine, Suez University, Egypt.
Hossam Hassan Kamel Hassan Surgical Oncology Department, Minia Oncology Center, Egypt.
Mohamed Mokhtar Surgical Oncology Department, Minia Oncology Center, Egypt.
Esayed Elmokadem General Surgery Department, Benha Teaching Hospital, Egypt.
Samia Hussein Medical Biochemistry Department, Faculty of Medicine, Zagazig University, Egypt.
Mayada El-metwally Ibrahim General Surgery Department, Faculty of Medicine, Suez University, Egypt.

DOI:

https://doi.org/10.31557/APJCC.2026.11.5.749

Keywords:

Therapeutic mammoplasty; Breast-conserving surgery; Oncoplastic breast surgery; Early-stage breast cancer

Abstract

Introduction: Conventional Breast-Conserving Surgery (BCS) is the standard management for early-stage breast tumors; however, cosmetic deformity and patient dissatisfaction may occur, particularly with larger tumors or unfavorable locations. This study aimed to compare therapeutic mammoplasty with conventional BCS regarding aesthetic outcome, patient and surgeon satisfaction, and postoperative complications.

Materials and Methods: This phase II comparative study included 60 female patients with early-stage breast cancer (stage I–II) treated between October 2023 and January 2026 at Suez University and Minia Oncology Center. Patients were enrolled into two groups. Group A included 30 patients who had therapeutic mammoplasty, while Group B included 30 patients who had conventional BCS.

Results: There were no statistically significant differences between the two groups regarding local recurrence and distant metastasis (P>0.05). Therapeutic mammoplasty was associated with significantly longer hospital stay and delayed initiation of adjuvant therapy (P < 0.001). However, aesthetic outcomes were significantly better in the therapeutic mammoplasty group, with 73.3% achieving good cosmetic results compared to 33.3% in the conventional BCS group (P=0.002). Additionally, the re-excision rate was significantly lower in the therapeutic mammoplasty group (P = 0.023). Moreover, patient and surgeon satisfaction were significantly higher following therapeutic mammoplasty. Furthermore, overall complication rates were significantly lower in the therapeutic mammoplasty group (P=0.004), with postoperative infection occurring more frequently after conventional BCS.

Conclusion: Therapeutic mammoplasty provides superior cosmetic outcomes, higher patient and surgeon satisfaction, and fewer overall complications than conventional BCS, supporting its use in selected cases with early-stage breast cancer.