Five-year Survival Predictors for Breast Cancer in Women: A Retrospective Cohort Study

Authors

DOI:

https://doi.org/10.31557/apjcc.2020.5.3.243-246

Keywords:

Breast neoplasm; Prognosis; Survival Analysis; Primary Health Care; Delayed Diagnosis.

Abstract

Objective: To analyze predictors of 5-year survival in women with breast cancer in the state of Sergipe.
Materials and methods: This is a retrospective cohort study. This study included 100 women aged between 21 and 77 years diagnosed with breast cancer undergoing adjuvant or neoadjuvant chemotherapy in a public tertiary hospital from August 2011 to December 2012. All women were followed up for 5 years or until the date of death. There was no loss in follow-up. Data were collected during the field visit to the specialized health unit and included demographic and socioeconomic variables, tumor staging at diagnosis, patient paths for presentation to health professionals, initial treatment in primary care and treatment. We used a three-stage model: the first (“patient delay”); the second (“delay in diagnosis”) and the third (“delay in treatment”). The statistical analysis was performed using the MedCalc version 18 statistical software. The study was approved by the Human Research Ethics Committee of the Federal University of Sergipe (CAAE: 0196.0.107.000-11). Written informed consent was obtained from all particip nts.
Results: Tumor staging [risk ratio (HR) = 3.41, p = 0.046] was an independent factor that affected the overall survival curve for women with breast cancer. The overall 5-year survival rates found for women with tumor staging IA-IIB compared to tumor staging IIIA-IV were 88.5% and 59.5%, respectively. Through binary logistic regression with forced entry method, it was evident that age (OR = 2.58, p = 0.050), delay in the first stage (OR = 2.57, p = 0.046) and tumor staging (OR = 3.99, p = 0.042) were predictors of mortality in women with breast cancer.
Conclusions: Our results highlight the need to strengthen health education actions in primary health care and the implementation of an organized and permanent screening program for the early detection of breast cancer.

Author Biographies

Carolina Tavares, Investigative Pathology Laboratory, Federal University of Sergipe, Aracaju, Brazil.

Nurse at the Emergency Unit of Hospital São José in Aracaju - SE. Post-graduation in Nursing in Intensive Care (UNIG / RJ) and Nursing in Nephrology (UNIFESP- in progress). High School by Colégio Brasília (2004). In the research area, he works on the following themes. Nursing, trauma and traumatic brain injury.

Andreia Vaez, Investigative Pathology Laboratory, Federal University of Sergipe, Aracaju, Brazil.

Graduation in Nursing from the State University of Western Paraná (UNIOESTE / 2003), Lato Sensu Specialization in Nursing with an emphasis on Adult Health (UNIOESTE / 2006), Master and Doctorate in Health Sciences from the Federal University of Sergipe (UFS / 2011- 2016). He is currently a professor in the Department of Nursing and Adjunct Professor III of the Nursing Discipline in Adult and Elderly Health. I do the Nursing Department at the Center for Biological Sciences and Health at the Federal University of Sergipe. Member of the research groups "Laboratory of Investigative Pathology (LPI).

Paulo Martins-Filho, Investigative Pathology Laboratory, Federal University of Sergipe, Aracaju, Brazil.

Associate Professor with an exclusive dedication regime at the Federal University of Sergipe (UFS). He has experience in epidemiology, statistics and systematic reviews and meta-analyzes in health. He is head of the Investigative Pathology Laboratory (LPI) and a permanent professor in the Postgraduate Program in Health Sciences at the Postgraduate Center in Medicine and the Postgraduate Program in Dentistry. For publications indexed in PubMed, type: Martins-Filho P. For citations in Scopus: Martins-Filho P.R.S. Scopus h index: 12; Google Scholar: 15.

Ana Almeida, São Paulo University, São Paulo, Brazil.

Graduated in Nursing from the University of São Paulo (1978), Master's in Nursing from the Federal University of Rio de Janeiro (1991) and PhD in Nursing from the University of São Paulo (1997). He is currently a visiting professor in the Graduate Program in Nursing at the Federal University of Paraíba and a senior professor at the University of São Paulo. She is a permanent professor in the Postgraduate Program in Public Health Nursing at the Ribeirão Preto College of Nursing at the University of São Paulo and in the Postgraduate Program in Public Health in the Frontier Region of UNIOESTE. Has experience in the area of Nursing, with emphasis on Obstetric Nursing, acting mainly on the following themes: nursing, breast cancer, women's health, breast cancer and breast cancer.

Leila Gonçalves, Postgraduate Program in Nursing, Federal University of Sergipe, Brazil.

Graduated in Nursing from the School of Nursing at the Federal University of Bahia (2000) and master's degree in Nursing, in the area of concentration of women's health from the Graduate Program of the UFBA School of Nursing (2001) and PhD in Sciences from the Interunits Program PhD Program of EE / EERP / USP (2013). She is currently an Adjunct Professor III of the Nursing Department at the Federal University of Sergipe. Has experience in Nursing, with emphasis on Nursing in Women's Health Care, acting mainly on the following themes: public health nursing, breast cancer, women's health, oncology nursing.

Downloads

Published

2020-08-15

How to Cite

Menezes, M., Tavares, C., Vaez, A., Martins-Filho, P., Almeida, A., & Gonçalves, L. (2020). Five-year Survival Predictors for Breast Cancer in Women: A Retrospective Cohort Study. Asian Pacific Journal of Cancer Care, 5(3), 243–246. https://doi.org/10.31557/apjcc.2020.5.3.243-246

Issue

Vol. 5 No. 3 (2020)

Section

Short Communication