Prognostic Factors for Survival in Patients with Gastric Cancer Treated at Two Public Health Institutions in Mexico

Alejandro Trujillo-Rivera; Clara Luz Sampieri; Linda Morales; Alejandra Montoya; Héctor Lamadrid-Figueroa

doi:10.31557/apjcc.2021.6.4.429-440

Authors

Alejandro Trujillo-Rivera Centro de Alta Especialidad “Dr. Rafael Lucio”, Xalapa, Veracruz, México
Clara Luz Sampieri Institute of Public Health, Veracruzana University, Av. Luis Castelazo Ayala S / N, Col. Industrial Animas 91190. Xalapa, Veracruz, Mexico
Linda Morales Instituto Nacional de Salud Pública, Cuernavaca, Morelos, México
Alejandra Montoya Instituto Nacional de Salud Pública, México, Cuernavaca, Morelos, México
Héctor Lamadrid-Figueroa Instituto Nacional de Salud Pública, Cuernavaca, Morelos, México

DOI:

https://doi.org/10.31557/apjcc.2021.6.4.429-440

Keywords:

Gastric cancer, adenocarcinoma, survival, prognostic factors

Abstract

Objective: To analyze the clinical records of patients with gastric adenocarcinoma, treated at two different public health institutions in Mexico to determine survival rates.
Methods: Cox proportional-hazards model was fitted to identify the factors involved in survival of patients.
Result: The results show that subjects aged 41 to 50 years of age had a 56% lower risk of death from gastric cancer compared to those <40 years of age. Asthenia and/or adynamia, weight loss and leukocytosis increased the risk of dying. The incidence of melena was found to be a protective factor for mortality.
Conclusion: At age <40 years, symptoms such as asthenia, adynamia and weight loss and leukocytosis are poor prognosis predictors in patients with gastric cancer. Melena seems to be a protective sign of gastric cancer mortality in Mexico. Given the low 5-year survival rate in patients with gastric cancer, further studies are necessary to explore the factors associated with survival to contribute to effective intervention.