Clinical and Pathological Features and Outcome of Patients with Salivary Gland Cancer a Single Centre Report

Authors

  • Mansour Ansari Breast Diseases Research Center, school of medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Shida Askarpour School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Hamid Nasrollahi Department of Radiation Oncology, Nemazee Hospital, School of Medicine, Shiraz University of Medical Sciences, Shiraz 71936, Iran.
  • Mohammad Mohammadianpanah Colorectal Research Center, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Niloofar Ahmadloo Radiation Oncology Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Shapoor Omidvari Breast Diseases Research Center, School of Medicine, Shiraz University of Medical Sciences Shiraz, Iran.
  • Ahmad Mosalaei Professor in Radiation Oncology, Radiation Oncology Department, school of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  • Sayed Hasan Hamedi Radiation Oncology Department, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
  • Mohammad Zare-Bandamiri Department of Epidemiology and Biostatistics, Faculty of Public Health. Kerman University of Medical Sciences, Kerman, Iran.

Keywords:

salivary gland, carcinoma, treatment

Abstract

Introduction: Salivary gland tumors are rare tumors that account for 3 to 4% of head and neck neoplasms. These tumors may arise from 6 major and numerous minor salivary glands. This study was designed to investigate the factors affecting the prognosis of salivary gland tumors.
Methods: This study is a retrospective descriptive study in which the records of patients with salivary gland tumors referred to the Radiotherapy and Oncology Center of Namazi Hospital from 2005 to 2015 were reviewed.
Results: 158 patients were included in this study with a mean age of 55.37 years. 49% of the patients were men. Adenoid Cystic Carcinoma was the most common histological type (30.57%) and Adenocarcinoma with a prevalence of 1.91% had the lowest prevalence rate in this study. 65.19% of salivary gland neoplasms in this study had parotid gland involvement and sublingual gland involvement had the lowest prevalence (3.8%). The results of survival analysis clearly illustrated that surgery, pathology type and stage was statistically significant in survival.
Discussion: Clinical, pathological and therapeutic factors in people with malignant salivary gland neoplasms have a significant relationship with their survival. controversies on treatment and outcome continues.

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Published

2022-06-14

Issue

Vol. 7 No. 2 (2022)

Section

Original Research