Association Between Autoimmune Thyroiditis and Thyroid Cancer: A Systematic Review of Studies in the Indian Population

Authors

  • Monalisha Saikia Borah Multidisciplinary Research Unit, Gauhati Medical College and Hospital, Guwahati-32, Assam, India. https://orcid.org/0000-0002-3121-2263
  • Ajanta Sharma Department of Microbiology, Gauhati Medical College and Hospital, Guwahati-32, Assam, India.
  • Tahmina Mazumder Computational Biology, MSMF, Narayana Health City, Bangalore 560099, India.
  • Amrit Pritam Bhuyan Mrbiologist, Guwahati-30, Assam, India.

Keywords:

Thyroid cancer, Autoimmune thyroiditis, Hashimoto's thyroiditis, Indian epidemiology, Indian population

Abstract

Background and Purpose: Thyroid cancer is a significant global health concern, and autoimmune thyroiditis, including Hashimoto's thyroiditis and chronic lymphocytic thyroiditis, has been suggested as a potential risk factor. This meta-analysis aimed to investigate the association between autoimmune thyroiditis and thyroid carcinoma in the Indian population.

Methods: A systematic search yielded 53 studies, of which six were included. Statistical analysis assessed the correlation between autoimmune thyroiditis and thyroid carcinoma.

Results: The analysis reveals a significant association between autoimmune thyroiditis and thyroid carcinoma in the Indian population, primarily driven by Hashimoto's thyroiditis.

Conclusion: This study underscores the relevance of autoimmune thyroiditis as a potential risk factor for thyroid carcinoma in India. Further research is needed to confirm these findings and elucidate the underlying mechanisms.

Published

2025-01-12

Issue

Section

Systematic Review and Meta-analysis: